Cancer

Researchers investigate whether a combination of fulvestrant and anastrozole will increase survival in HR+breast-cancer patients. Breast cancer is a complex disease that is difficult to treat. There are different types of breast cancer and each type requires its own unique treatment strategy. There are two broad categories of breast cancer: hormone receptor positive (HR+) breast
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Researchers evaluated an immunotherapy-chemotherapy combination cream in the prevention of skin cancer following precancerous lesions in sun-damaged skin. Despite widespread awareness of the need to protect skin from the sun, squamous cell carcinoma (SCC) of the skin is the second most common cancer in the United States, and its incidence continues to rise. Skin cancer
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A recent study in Circulation investigated the mechanisms underlying the negative effects of chemotherapy for breast cancer on heart function. Cardiovascular complications are the leading cause of morbidity and mortality among cancer survivors. These complications, including impaired heart function, are thought to be caused, in part, by the anti-cancer therapy. Trastuzumab (Herceptin) and heart dysfunction
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Reading Time: 3 minutes The Journal of Physiology published research that highlights the link between exercise and decreased tumour growth in colon cancer.   As time passes by, the baby-boomer generation increases in age and consequently, the global population’s median age also increases. With older age, comes a higher risk of chronic diseases. Cancer, specifically
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Reading Time: 3 minutes A new study by Australian researchers investigated why middle-aged women increasingly drink alcohol despite the well-known association between alcohol and breast cancer. According to the International Agency for Research on Cancer, alcohol consumption increases the risk of breast cancer. For every 10g (around one drink) of alcohol an adult woman consumes
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Reading Time: 2 minutes A recent study explored the differences in risk-management behaviours between women of various races who are at high risk of developing breast cancer. Managing several medical conditions is largely influenced by personal, social, genetic, environmental, and psychological determinants of health. These factors vary by race, leading to racial disparities that are
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Reading Time: 3 minutes A recent study investigated tongue microbial populations as a potential tool for the early detection of pancreatic cancer. Pancreatic cancer is among the deadliest cancer types. This disease causes hundreds of thousands of deaths every year, ranking seventh for the number of fatalities from cancer. Pancreatic cancer occurs more often in
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Reading Time: 2 minutes A recent study explored how amplification of the androgen receptor in prostate cancers leads to drug resistance and identified an important protein in this biological pathway. The prostate is a gland of the male reproductive system that plays a role in secreting fluids which make up semen. Normal development of the
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A new study published in PLOS Medicine investigated how obesity contributes to the development of kidney cancer. Multiple studies have demonstrated a consistent positive association between obesity and kidney cancer, regardless of risk factors for this cancer such as hypertension. This relationship have been found to be stronger in women, although it has also been
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A recent study analyzing the receptor that leads to nausea could be crucial in the development of drugs to reduce chemotherapy side effects. Most currently used cancer drugs are known to cause many chemotherapy side effects. These unpleasant side effects are sensed through a class of receptors called neurokin 1 receptor (NK1R). Pharmacological targeting of these
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A recent study investigated why immunotherapy for breast cancer is not as effective as a cancer treatment. Despite the recent advancements in immunotherapy and the new era of personalized medicine to treat different forms of cancer, breast cancer has proven to be a difficult opponent for this new therapy. Previous trials have shown that immunotherapy
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Past methods for antitumor therapies have focused on enhancing systemic immune activity. Yale University researchers have highlighted developments in a more recent approach to cancer immunotherapy that may result in more effective treatments. Since its inception, cancer research has largely been based on the premise of enhancement therapies: immune system boosting treatments that increase the
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Many cancer patients find that they develop cognitive problems as they become ill. A new study found that aspirin could limit cognitive problems in mice with cancer. Almost half of cancer patients with solid tumors develop cognitive problems, including problems with learning, concentration, and memory. Some of these problems can remain decades after successful cancer
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New research from Brigham and Women’s Hospital in the United States explores how genetics impacts the effects of vitamin E in cancer. Nearly half (48%) of all Americans take daily vitamin supplements. However, clinical data supporting the use of many of these supplements is severely lacking. One such vitamin often supplemented is vitamin E (also
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A study in Canada in collaboration with scientists from the United Kingdom tested the accuracy of a cervical cancer test based on epigenetics. Infection with the HPV virus is associated with the development of cervical cancer, as research has shown that virtually all cervical cancer patients have tested positive for HPV virus. However, not all
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Hot flashes during menopause are usually more severe in breast cancer survivors than in the general female population. Hormone-replacement therapy is a traditional treatment for hot flashes, but many women cannot tolerate these drugs. A recent study explored the use of oxybutynin for reducing hot flashes. Hot flashes are a common symptom of menopause. Menopause
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