Cancer

Results from the recent BEACON CRC trial highlights a new triple therapy drug combination for the treatment of advanced bowel cancer. Up to 15% of patients with advanced bowel cancer have a mutation in the BRAF gene. These patients have a poor prognosis for survival, especially in those who fail initial standard chemotherapy. These patients
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Researchers at Oregon State University have improved techniques that use magnetic nanoparticles to kill cancer cells with heat. The improved magnetic nanoparticles – particles that measure close to one-billionth of a meter- created by these researchers generate heat in the cancer cells when activated using an alternating magnetic field. This form of cancer treatment is
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Researchers have developed a computer algorithm that might be able to accurately predict cancer outcomes in patients. Cancer is a group of complex diseases, characterized by the abnormal growth of cells. One of the major challenges of caring for cancer patients is the inability to accurately predict long-term health outcomes. Specifically, it is difficult for
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New research investigates the effects of using turmeric as an alternative to traditional chemotherapy for bone cancer. While most cancers primarily affect older adults, osteosarcomas, which are the most common type of bone cancer, mostly affects children and youths. Chemotherapy is a standard treatment for bone cancer because it is difficult to remove cancerous tumours
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Researchers train cancer-sniffing dogs to distinguish blood samples from lung cancer patients Lung cancer is the leading cause of cancer-related death in men and women worldwide. People diagnosed with late-stage lung cancer have a less favourable prognosis and lower chances of survival. For non-small cell lung cancer (NSCLC), the five-year survival rate is 92 percent
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Prostate cancer is one of the most common cancers in men. On-going research programs are searching for better ways of diagnosing and treating this serious disease. Prostate cancer is the second most common cancer in men. Prostate cancer can be treated if caught early enough, however, there are few effective treatments for advanced prostate cancer.
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A new study in the Journal of Experimental Medicine investigated the molecular factors behind the gender disparity in liver cancer development. According to a 2108 study based on data from the International Agency for Research on Cancer, liver cancer is the fourth most lethal form of cancer worldwide. Hepatocellular carcinoma (HCC), the most common form
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Researchers investigate whether a combination of fulvestrant and anastrozole will increase survival in HR+breast-cancer patients. Breast cancer is a complex disease that is difficult to treat. There are different types of breast cancer and each type requires its own unique treatment strategy. There are two broad categories of breast cancer: hormone receptor positive (HR+) breast
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Researchers evaluated an immunotherapy-chemotherapy combination cream in the prevention of skin cancer following precancerous lesions in sun-damaged skin. Despite widespread awareness of the need to protect skin from the sun, squamous cell carcinoma (SCC) of the skin is the second most common cancer in the United States, and its incidence continues to rise. Skin cancer
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A recent study in Circulation investigated the mechanisms underlying the negative effects of chemotherapy for breast cancer on heart function. Cardiovascular complications are the leading cause of morbidity and mortality among cancer survivors. These complications, including impaired heart function, are thought to be caused, in part, by the anti-cancer therapy. Trastuzumab (Herceptin) and heart dysfunction
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Reading Time: 3 minutes The Journal of Physiology published research that highlights the link between exercise and decreased tumour growth in colon cancer.   As time passes by, the baby-boomer generation increases in age and consequently, the global population’s median age also increases. With older age, comes a higher risk of chronic diseases. Cancer, specifically
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Reading Time: 3 minutes A new study by Australian researchers investigated why middle-aged women increasingly drink alcohol despite the well-known association between alcohol and breast cancer. According to the International Agency for Research on Cancer, alcohol consumption increases the risk of breast cancer. For every 10g (around one drink) of alcohol an adult woman consumes
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Reading Time: 2 minutes A recent study explored the differences in risk-management behaviours between women of various races who are at high risk of developing breast cancer. Managing several medical conditions is largely influenced by personal, social, genetic, environmental, and psychological determinants of health. These factors vary by race, leading to racial disparities that are
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Reading Time: 3 minutes A recent study investigated tongue microbial populations as a potential tool for the early detection of pancreatic cancer. Pancreatic cancer is among the deadliest cancer types. This disease causes hundreds of thousands of deaths every year, ranking seventh for the number of fatalities from cancer. Pancreatic cancer occurs more often in
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Reading Time: 2 minutes A recent study explored how amplification of the androgen receptor in prostate cancers leads to drug resistance and identified an important protein in this biological pathway. The prostate is a gland of the male reproductive system that plays a role in secreting fluids which make up semen. Normal development of the
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A new study published in PLOS Medicine investigated how obesity contributes to the development of kidney cancer. Multiple studies have demonstrated a consistent positive association between obesity and kidney cancer, regardless of risk factors for this cancer such as hypertension. This relationship have been found to be stronger in women, although it has also been
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A recent study analyzing the receptor that leads to nausea could be crucial in the development of drugs to reduce chemotherapy side effects. Most currently used cancer drugs are known to cause many chemotherapy side effects. These unpleasant side effects are sensed through a class of receptors called neurokin 1 receptor (NK1R). Pharmacological targeting of these
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