Clinical Trials & Research

We are all familiar with the term lifespan. However, someone with a long lifespan does not necessarily have a long healthy quality of life. A relatively new term gaining importance as we live longer is healthspan. Healthspan refers to the length of time a person is healthy, not just alive. As we age, some people
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Researchers in the Netherlands investigated whether a common blood pressure drug could be used as a medication for Alzheimer’s disease. Dementia describes a group of symptoms including memory loss, a decline in thinking processes, personality changes, and inappropriate behavior. There are several different types of dementia. Alzheimer’s disease is the most common cause of progressive
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A clinical trial of dulaglutide reported impressive results in cardiovascular events prevention among people with type 2 diabetes. Individuals with diabetes have a two times higher risk of cardiovascular events, such as heart attacks and strokes, and around 40% develop kidney disease. Dulaglutide is a glucagon-like peptide-1 analog that increases levels of incretin. Incretin is
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Researchers have developed a new sequencing method to help diagnose acute brain and spinal cord infections. Infections that affect the brain and spinal cord, such as meningitis and encephalitis, can lead to inflammation. There are many possible causes of these diseases, including bacteria, viruses, fungi, and parasites. Symptoms are widely varied and can include sudden
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A recent study investigated the benefits of Enzalutamide, a new drug treatment for prostate cancer, on survival outcomes. Prostate cancer is commonly treated with testosterone suppression as first-line therapy with the addition of a nonsteroidal antiandrogen drug, to help reduce testosterone levels, as standard care. Unfortunately, patients can develop resistance to the nonsteroidal antiandrogen drugs,
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In this study, researchers examine the effects of a drug, fluoxetine, in improving the functional ability of those facing stroke recovery. Stroke affects many worldwide. Disability is one of the debilitating effects after a stroke.  It is estimated that 6.5 million people worldwide are affected by post-stroke disability. Usually, post-stroke recovery involves treating depression and
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Researchers at Virginia Tech are testing a new drug for chronic pain treatment that may avoid the addictive effects of opioids. Non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin are commonly used for mild and moderate generalized pain but may have limited effectiveness in alleviating chronic nerve pain. NSAIDs inhibit the activity of cyclooxygenase enzymes responsible
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Our Reader Score [Total: 0 Average: 0] Despite the rising number of peanut-allergic children in North America, no FDA approved food allergy treatment is available. A recent phase-3 trial tested a new oral peanut allergy treatment in children and adolescents. There is currently no treatment for allergy symptoms caused by peanut proteins. Peanut-allergic patients are
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Our Reader Score [Total: 0 Average: 0] A dendritic cell-based vaccine targeting HER2 has shown immense promise in a phase-1 clinical trial, as presented at the CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference. HER2 is a type of receptor that is found on the surface of certain cancer cells. Specific hormones and growth factors can bind to
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Our Reader Score [Total: 7 Average: 5] A first-in-human clinical trial of a new drug has generated promising results in reducing vascular calcification of hemodialysis patients. Vascular calcification is the leading cause of death in patients with end-stage renal disease undergoing hemodialysis. According to The US Renal Data System, nearly 50% of patients with end-stage
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Our Reader Score [Total: 2 Average: 3] A group of researchers in the US modified the existing chemotherapy with humanized antibodies to improve lung cancer survival rates. Lung cancer is the leading cause of death from cancer in Canada. According to The Canadian Cancer Society, about 28,600 Canadians were diagnosed with lung cancer in 2017.
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Our Reader Score [Total: 0 Average: 0] A clinical trial of stroke treatments showed that giving three antiplatelet therapy drugs had no benefit over two, and was associated with more bleeding. Recent large-scale clinical trials have shown that starting treatment with two antiplatelet therapy drugs after a stroke, rather than just one, reduces the risk
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Our Reader Score [Total: 1 Average: 5] Stem cell clinical trials have the potential to treat and cure genetic and degenerative diseases. However, many recent trials have sacrificed scientific quality and health safety to push quicker clinical trials. Concerned researchers advocating for better clinical trial have proposed new guidelines to deter substandard clinical trials. Stem
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