Clinical Trials & Research

Our Reader Score [Total: 0 Average: 0] A dendritic cell-based vaccine targeting HER2 has shown immense promise in a phase-1 clinical trial, as presented at the CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference. HER2 is a type of receptor that is found on the surface of certain cancer cells. Specific hormones and growth factors can bind to
0 Comments
Our Reader Score [Total: 2 Average: 3] A group of researchers in the US modified the existing chemotherapy with humanized antibodies to improve lung cancer survival rates. Lung cancer is the leading cause of death from cancer in Canada. According to The Canadian Cancer Society, about 28,600 Canadians were diagnosed with lung cancer in 2017.
0 Comments
Our Reader Score [Total: 0 Average: 0] A clinical trial of stroke treatments showed that giving three antiplatelet therapy drugs had no benefit over two, and was associated with more bleeding. Recent large-scale clinical trials have shown that starting treatment with two antiplatelet therapy drugs after a stroke, rather than just one, reduces the risk
0 Comments
Our Reader Score [Total: 1 Average: 5] Stem cell clinical trials have the potential to treat and cure genetic and degenerative diseases. However, many recent trials have sacrificed scientific quality and health safety to push quicker clinical trials. Concerned researchers advocating for better clinical trial have proposed new guidelines to deter substandard clinical trials. Stem
0 Comments
Our Reader Score [Total: 1 Average: 4] Most treatments for multiple sclerosis concentrate on managing symptoms and slowing disease progression. A recent phase-3 trial investigated whether natalizumab is effective in treating secondary progressive multiple sclerosis. Canada has one of the highest incidences of multiple sclerosis (MS) worldwide. An autoimmune disease, MS targets the protective covering
0 Comments
Our Reader Score [Total: 0 Average: 0] The results of a phase-3 trial were recently published comparing the effectiveness of postoperative chemotherapy with chemoradiotherapy for gastric cancer. Gastric carcinoma is a form of cancer that originates in the lining of the stomach. This form of cancer is rare in comparison to other types of cancer.
0 Comments
Our Reader Score [Total: 1 Average: 5] Investigator brochures are key documents in the regulatory approval process before initiating clinical trials. A recent study by German and Canadian researchers investigated just how effective these documents are at enabling accurate risk-benefit assessments. The main purpose of early-phase clinical research is to establish the safety and dosing
0 Comments
Our Reader Score [Total: 0 Average: 0] In a recent study, researchers examined the effects of amobarbital and N-acetylcysteine on post-traumatic osteoarthritis in injured joints. Injury to load-bearing joints such as the knees or ankles can result in posttraumatic osteoarthritis (PTOA), a condition in which the shock-absorbing and friction-reducing joint cartilage breaks down over time.
0 Comments
Our Reader Score [Total: 0 Average: 0] Researchers attempt to identify a therapeutic target that encourages respiratory muscle relaxation to provide asthma relief. Asthma causes respiratory problems, which can manifest as wheezing and chest tightness. It is a common affliction that affects about 10% of the US population. There has been much research focused on
0 Comments
Our Reader Score [Total: 0 Average: 0] Safety is an important aspect of the development of new drugs. Researchers are evaluating the safety and effectiveness of using RNA drugs to deliver instructions to cells to create proteins that are deficient in rare diseases. Messenger ribonucleic acid (mRNA) is an important molecule in the production of
0 Comments
Our Reader Score [Total: 0 Average: 0] Tuberculosis is a communicable respiratory disease. A group of researchers led by Maeve Lalor conducted a cohort study to determine household transmission of tuberculosis in England by combining epidemiologic and molecular strain typing data. Tuberculosis is a communicable respiratory disease prevalent in some third world countries. In first
0 Comments
Our Reader Score [Total: 0 Average: 0] A recent study explored the antibacterial effects of modified forms of vancomycin on antibiotic-resistant bacteria. The results suggest C1-aminomethylene vancomycin may be an effective agent against methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic-resistant bacteria. The ability of bacterial strains to acquire resistance to antibiotics faster than antibacterial therapies
0 Comments
Our Reader Score [Total: 1 Average: 5] Researchers from Duke University in North Carolina produced pathogen-resistant crops without compromising the plant’s yield and fitness. Plants are commonly attacked by microbial, viral or fungal pathogens. Improving crop production involves the applications of pesticides. In recent years, genetically modified pathogen-resistant crops that express a high level of
0 Comments