Clinical Trials & Research

A new study published in Science Advances discovers that blocking Flt1 and Nrp1 from interacting with vascular endothelial growth factor A (VEGFA) in the skin epidermis prevents psoriasis development. Three percent of the world’s population is affected by psoriasis, a skin inflammatory disorder that causes raised, red, scaly patches to appear on the skin.  It
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New study reports the improved efficacy of the tuberculosis vaccine by changing the vaccination method. The World Health Organization reported that in 2018 a total of 1.5 million died from Tuberculosis (TB) worldwide, making it the leading cause of death from a single infectious agent.  The WHO also lists multidrug-resistant TB as a health security
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Patients with non-celiac wheat sensitivity show characteristic miRNA expression patterns that may contribute to the diagnosis of this condition. Wheat is the most widely grown crop in the world. It is consumed in a variety of foods including bread, pasta, noodles, bulgur, and couscous. Gluten is a protein found in wheat, barley, rye, and other
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Over time, some types of cancers such as melanoma, lung cancer, and kidney cancer present with symptoms of inflammation and immunosuppressed tumour microenvironments (the structural environment around a malignant tumour).An immunosuppressed tumour microenvironment inhibits the activity of the immune system, specifically  T-cells: a key player in the body’s immune response. Immunotherapy is a type of
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A new study explains why people may be allergic to some skincare products. Over the past two hundred years, industrialization has dramatically increased the number of chemicals humans are exposed to, whether intentional (e.g., from cosmetics, fragrances, consumer products, etc.) or not (e.g., from pollution). The incidence of allergic contact dermatitis – a skin rash
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This study focuses on protecting babies in the neonatal intensive care unit from Staphylococcus aureus. Staphylococcus aureus (S. aureus) is a bacterium that can be found on human skin. Infections with S. aureus can be serious and life-threatening, making it a significant concern in the neonatal intensive care unit (NICU). A recent study investigated whether
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A recent Canadian study reveals shaky links between human genetics and disease risk prediction. Genome-wide association (GWA) studies are a relatively new approach to identify genes involved in human disease. GWA studies involve scanning the entire human genome for specific variations called single nucleotide polymorphisms (SNPs). Highly significant SNPs will occur more frequently in people
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A recent study has concluded that exposure to a common pesticide increases the risk of all-cause mortality and cardiovascular mortality. Although the study has limitations, its authors call for urgent follow-up. The study focused on a class of pesticides called pyrethroids. People use these chemicals in agriculture and for residential pest control. Pyrethroids also appear
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A recent study found that migraine patients have a different response to nitroglycerin compared to non-migraine patients. A migraine is a disorder characterized by recurrent headaches that range from moderate to severe. The physiology behind migraine is complex and the mechanisms are not yet fully understood. Nitroglycerin is a chemical that is used for its
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